Uppsala: Postdoktor - Bakterier för att bekämpa vedrötsvampar

Vill du arbeta med datorsimuleringar av enzymer, med stöd av kompetenta och trevliga kollegor i en internationell miljö? Vill du ha en arbetsgivare som satsar på ett hållbart medarbetarskap och erbjuder trygga, förmånliga arbetsvillkor? Välkommen att söka anställning som postdoktor på Uppsala universitet.

Institutionen för cell- och molekylärbiologi är indelad i sju forskningsprogram som alla fokuserar på olika områden inom cell- och molekylärbiologi: beräkningsbiologi och bioinformatik, mikrobiologi och immunologi, molekylärbiologi, molekylär biofysik, molekylär evolution, molekylär systembiologi och strukturbiologi. Den vetenskapliga grunden till vad vi gör ligger i biologi, men vår forskning överlappar med andra områden såsom medicin, datavetenskap, matematik, kemi, ingenjörsvetenskaper och fysik. Institutionen har över 200 anställda med runt 60 doktorander. Läs gärna mer om verksamhetens arbete på https://icm.uu.se. Denna tjänst är tillgänglig inom Johan Åqvists forskargrupp vid programmet för beräkningsbiologi och bioinformatik. Forskningen är inriktad på datorsimuleringar av enzymkatalys, speciellt avseende enzymevolution och adaption, i samarbete med experimentella grupper.

Arbetsuppgifter
Forskningsprojektet omfattar datorbaserad analys av enzymers evolution och adaption till extrema miljöer. Arbetsuppgifterna inkluderar datorsimuleringar med molekyldynamiska, EVB- och QM/MM-metoder, fria-energiberäkningar, molekylär dockning, bioinformatisk analys och modellering av proteinsruktur, samt programutveckling.

Kvalifikationskrav
Doktorsexamen i beräkningskemi, strukturbiologi, biofysik eller en utländsk examen som bedöms motsvara doktorsexamen inom dessa områden. Examen ska vara uppfyllt senast vid tidpunkten då anställningsbeslutet fattas. Främst bör den komma ifråga som har avlagt examen för högst tre år sedan. Vid beräkning av ramtiden om tre år är utgångspunkten sista ansökningsdag. Om det finns särskilda skäl kan sådan examen ha avlagts tidigare. Med särskilda skäl avses ledighet på grund av sjukdom, föräldraledighet, förtroendeuppdrag inom fackliga organisationer, etc.

Dokumenterad erfarenhet av beräkningskemi och strukturbiologi, demonstrerad vetenskaplig skicklighet, uppvisad i vetenskapliga publikationer samt presentationer på nationella och internationella konferenser. Projektet omfattar samarbete mellan olika discipliner, så en god förmåga att samverka med andra personer är därför ytterst viktigt. Stor vikt kommer även att läggas vid personliga färdigheter såsom kommunikations- och samarbetsfärdigheter, förmåga att arbeta självständigt samt vetenskaplig mognad och kreativitet. En förutsättning för tjänsten är att du är flytande i engelska, både i tal och skrift, då tjänsten är i en internationell miljö.

Önskvärt/meriterande i övrigt
Erfarenhet av molekyldynamiksimulering, modellering av enzymreaktioner, strukturbioinformatik, och experimentell biokemi. 

Om anställningen 
Anställningen är tidsbegränsad i minst två och högst tre år enligt centralt kollektivavtal. Omfattningen är heltid. Tillträde 2024-11-01 eller enligt överenskommelse. Placeringsort: Uppsala. 

Upplysningar om anställningen lämnas av: Johan Åqvist, +4618 471 41 09, Johan.Aqvist@icm.uu.se.

Välkommen med din ansökan senast den 1 oktober 2024, UFV-PA 2024/2877. 

Uppsala universitet är ett brett forskningsuniversitet med stark internationell ställning. Det yttersta målet är att bedriva utbildning och forskning av högsta kvalitet och relevans för att göra skillnad i samhället. Vår viktigaste tillgång är alla 7 600 anställda och 53 000 studenter som med nyfikenhet och engagemang gör Uppsala universitet till en av landets mest spännande arbetsplatser.


Läs mer om våra förmåner och hur det är att jobba inom Uppsala universitet
https://uu.se/om-uu/jobba-hos-oss/


Anställningen kan komma att säkerhetsprövas. Vid säkerhetsprövning är en förutsättning för anställning att sökande blir godkänd.


Vi undanber oss erbjudanden om rekryterings- och annonseringshjälp.


Ansökan tas emot i Uppsala universitets rekryteringssystem.

Department of Animal Biosciences
Come join our spider silk team! In this project we will elucidate the secrets behind how spider spin their silks (one individual can spin up to seven different silk types!). As a research group we are interested in how spiders have solved problems related to protein production, storage and polymerization, and develops methods for producing the material by recombinant protein production and biomimetic fiber spinning. The group has taken an interest in determining the biology of the silk glands in order to pave ways for making better artificial spider silk fibers. Our group has generated a significant amount of state-of-the-art data from genomic sequencing, scRNAseq of dissociated glands, spatial transcriptomics (10XVisium) and proteomics. Now we are looking for a postdoc with a keen interest in bioinformatics that will process the data to elucidate what the structure and function of the different glands are, what the composition of the respective silk types is, and investigate similarities and differences between these. The project has been generously funder by ERC, KAW and Olle Engkvist Stiftelse. We are also supported by SciLifeLab Bioinformatics long term support.
About the position
You will be part of an excellent team of several PhD students, Postdocs and Researchers working on different projects related to biotechnological methods for producing recombinant silk proteins, characterization of these, spinning of fibers, protein engineering, material characterization, machine learning and bioinformatics to understand the transcriptome profile of the silk glands. The specific project focuses on the analysis and integration of single-cell RNA sequencing, bulk RNA sequencing, spatial transcriptomics, and proteomics data. Additionally, it involves conducting comparative analyses to link variations in the mechanical properties of silk across different spider species to their genetic background, considering both gene expression and sequence variation. 

The applicant is expected to actively pursue the project, keep updated with the literature, interact with the other team members, be active at journal clubs and meetings, present results in a pedagogic way, write reports and papers, and have a positive attitude. You will be responsible for planning the work and executing the analyses. Teaching of undergraduates and PhD students may be part of the duties.

Your profile
A PhD in a relevant subject obtained within the past three years, and several publications in international peer-reviewed journals and at least one as first author are required.

Excellent knowledge in English is a requirement (at least C1 level in reading, writing and listening).

Previous experience of at least one of the techniques that will be used in the project is required.

As a person you are positive, ambitious, thorough, and able to keep deadlines. 

About us
The spider silk biomimetics group at SLU is highly productive and successful group that has secured several grants from the European Research Council. Recently, the group has been awarded significant research grants from Olle Engkvist Stiftelse and Knut and Alice Wallenberg Foundation which vouch for a continued high level of research activities. We are dedicated, ambitious and have a friendly and helpful atmosphere. You can read more about us here: https://www.slu.se/en/ew-cv/anna-rising/

The department is part of the Faculty of Veterinary Medicine and Animal Science and is responsible for education and research in several basic and applied areas. These areas include anatomy, physiology, biochemistry, pathology, pharmacology, toxicology, genetics, breeding, immunology, bacteriology, virology, parasitology, epizootology, comparative medicine, food safety, bioinformatics and One Health. Our research covers everything from production animals to sports and pet animals, laboratory animals and wild animals. The department's researchers work on the entire scale from molecular mechanisms and microbiology to the structure, function and behaviour of animals, and how these are affected by breeding, physical activity, care, production, stress, environmental factors and diseases.

For more information about the department visit: https://www.slu.se/en/departments/Animal-Biosciences/

Read more about our benefits and working at SLU by visiting: https://www.slu.se/en/about-slu/work-at-slu/

Location:
Uppsala

Form of employment:
Temporary employment 24 months, with the possibility of extension.

Scope:
100%

Start date:
As agreed

Application:
Applicants must attach three or four documents:


• CV including contact information, publication list and contact information for at least two references that know the applicant and his or her qualifications.
• Description of previous and ongoing research and a justification for the applicant's relevance to obtain the position. Description of preliminary research ideas are welcome but not required. (Maximum two A4 pages.)
• Copy of diploma or link to or copy of doctoral dissertation.
• If the applicant is not a native English speaker, an official certificate stating the level of English proficiency is required.

Please submit your application before deadline 26 August 2024. You can submit your application by clicking the button below.

Union representatives:
https://internt.slu.se/en/my-employment/employee-associations/kontaktpersoner-vid-rekrytering/


The Swedish University of Agricultural Sciences (SLU) has a key role in the development for sustainable life, based on science and education. Through our focus on the interaction between humans, animals and ecosystems and the responsible use of natural resources, we contribute to sustainable societal development and good living conditions on our planet. Our main campuses are located in Alnarp, Umeå and Uppsala, however, the university also operates at research stations, experimental forests and teaching sites throughout Sweden.

SLU has around 3,000 employees, 5,000 students and doctoral students and a turnover of over SEK 3 billion. We are investing in attractive environments on all of our campuses. We strive to provide a work environment characterised by inclusivity and gender equality, where different experiences generate conversations between people and pave the way for science, creativity and development. Therefore, we welcome applications from people with diverse backgrounds and perspectives.

Department of Ecology
PhD position based at the Dept of Ecology, part of the Ecology Centre of the Swedish University of Agricultural Sciences (SLU), in Uppsala. The student will join a stimulating and dynamic research environment and have access to an extensive national and international network with colleagues who focus on multiple aspects of sustainable agriculture. At the Ecology Centrum, we generate knowledge on how land use and climate affects plants, nutrient cycling, greenhouse gas balance, and animals, and develop sustainable solutions for the future.

Read more about our benefits and what it is like to work at SLU at https://www.slu.se/en/about-slu/work-at-slu/

Modelling plant-environment and plant-plant interactions
Biology with specialization in ecology
Description:
Are you looking for an exciting PhD position on plant-environment and plant-plant interactions, using mechanistic models? Do you want to identify management practices that minimize negative environmental impacts and are robust to climate change? Are you highly motivated to undertake a PhD training and actively pursue an academic career?

Crop production needs to be transformed. Agriculture can be made more sustainable and resilient by relying more on ecosystem services provided by biodiversity and less on external inputs such as fertilizers and pesticides. These ecosystem services depend on crop traits and climate and soil conditions. This doctoral project will employ mathematical models based on ecological and physiological mechanisms to look at advantages and disadvantages of different management practices for primary production, climate change adaptation, and reduced environmental impacts.

As PhD student in Biology with specialization in Ecology, the student will carry out supervised research leading to a PhD thesis and take a minimum 30 higher education credits in courses.

Qualifications:
The required qualification is at least 240 higher education credits, including at least 60 credits at 2nd cycle education. The credits can be in engineering, earth and environmental sciences, physics, applied mathematics, natural sciences, or related fields. Written and oral proficiency in English is required. Interest and previous experience in developing mechanistic models coupling plants, biogeochemical cycles, ecosystems, and environmental conditions, as well as documented strong quantitative and programming skills (in C, MatLab, R, Python, or other languages for data analysis and model implementation) are merits.

The application, written in English, must contain, in a separate file, a statement of your scientific interests and motivation for applying to this specific position, clarifying your interests in this project and experience with mechanistic models and quantitative approaches (max 5000 characters). The selection among the eligible applicants is based on their capacity to benefit from the training, as well as their creativity, initiative, and independence. The selection is made with reference to the written application and an interview. Particular emphasis is placed on your written motivation.

Place of work:      
Uppsala, Sweden.

Forms for funding or employment:
Employment (4 years).

Starting date:
According to agreement. 

Application:
Click the “Apply” button to submit your application. The deadline is 2024-10-30. Applications via email cannot be considered.

The application, written in English, must contain

-         a statement of your scientific interests and motivation for applying to this position, specifying your interests and experience with mechanistic models (max 5000 characters)

-         Curriculum Vitae including any publication

-         copies of previous university degrees and transcripts of completed courses

-         copy of the dissertation for masters or undergraduate degree

-         contact information to at least 2 reference persons

-         certification of English language knowledge equivalent to at least English B/English 6 (see https://www.universityadmissions.se/en/entry-requirements/english-language-requirements)

Applicants invited to interview must submit attested copies of their degree certificate, or a transcript of records from previous first and second-cycle studies at a university or higher education institution. Applicants who are not Swedish citizens need to submit an attested copy of their passport’s information page containing their photograph and personal details.

Read about the PhD education at SLU at www.slu.se/en/education/programmes-courses/doctoral-studies/

Academic union representatives:
https://internt.slu.se/en/my-employment/employee-associations/kontaktpersoner-vid-rekrytering/


The Swedish University of Agricultural Sciences (SLU) has a key role in the development for sustainable life, based on science and education. Through our focus on the interaction between humans, animals and ecosystems and the responsible use of natural resources, we contribute to sustainable societal development and good living conditions on our planet. Our main campuses are located in Alnarp, Umeå and Uppsala, however, the university also operates at research stations, experimental forests and teaching sites throughout Sweden.

SLU has around 3,000 employees, 5,000 students and doctoral students and a turnover of over SEK 3 billion. We are investing in attractive environments on all of our campuses. We strive to provide a work environment characterised by inclusivity and gender equality, where different experiences generate conversations between people and pave the way for science, creativity and development. Therefore, we welcome applications from people with diverse backgrounds and perspectives.

Gemensamma verksamhetsstödet
Till SLU:s miljöenhet söker vi nu en miljökoordinator som ska bidra till SLU:s miljöarbete. Vi söker dig som vill bli en del av miljöenhetens team och driva miljöfrågorna inom SLU framåt.

Om jobbet
Som miljökoordinator kommer du att arbeta brett med miljöfrågor. Du kommer att arbeta med allt från det övergripande miljöledningsarbetet, SLU:s miljömål, uppföljningar och rapporteringar, till kontakter med andra myndigheter och lärosäten. Mycket av arbetet handlar om att samordna insatser där du kommer att arbeta stödjande och rådgivande till verksamheten kopplat till interna miljöfrågor för hela SLU. Som miljökoordinator kan du komma att utföra en bred palett av arbetsuppgifter som exempelvis att bidra i miljökommunikation, identifiera och följa upp miljöaspekter, stödja verksamheten avseende lagkrav och lagefterlevnad inom miljöområdet, myndighetsrapporteringar samt samordning och genomförande av interna miljörevisioner. Resor inom Sverige förekommer.

Din bakgrund 
Vi söker dig som har en naturvetenskaplig akademisk utbildning och har ett stort intresse för miljöfrågor. Du bör vara insatt i och ha kunskap om miljöledningsarbete. Du har goda kunskaper i svenska och engelska både i tal och skrift, har god datorvana och behärskar Officepaketet. Meriterande för tjänsten är även om du har kunskaper inom miljölagstiftningen, miljöledningsstandarden ISO 14001:2015, kemikalier och miljöriskbedömningar, miljörevisionsarbete samt har erfarenhet av att arbeta med miljökommunikation. Det är också meriterande om du har erfarenhet av att hantera och bearbeta större datamängder för sammanställning, analys och rapportering. 

Som person är du utåtriktad och har lätt för att kommunicera och samarbeta med andra. Arbetet kräver såväl stort engagemang, struktur, noggrannhet och förmåga att planera och organisera arbetet på ett effektivt sätt. Vi kommer att lägga stor vikt vid personlig lämplighet.

Om oss
Miljöenheten arbetar aktivt för att öka kunskapen, medvetenheten och engagemanget internt inom universitetet för miljöfrågor. Miljöenheten initierar och följer upp övergripande miljömål och ansvarar för samordning och kommunikation om SLU:s miljöledningsarbete. Inom miljöenheten ryms även arbete med kemikaliesäkerhet, fysisk arbetsmiljö och biosäkerhet samt hållbarhetsarbete kopplat till Agenda 2030. Miljöenheten är delaktig i många processer, däribland miljörelaterade myndighetskontakter, samordning av interna och externa miljörevisioner samt tillhandahållande av olika verktyg för organisationen.

Infraavdelningen är en av tretton avdelningar inom verksamhetsstödet vid Sveriges lantbruksuniversitet. Infra bedriver verksamhet på universitetets huvudorter Umeå, Uppsala och Alnarp. Avdelningen har ca 120 medarbetare och omsätter ca 100 Mkr. Verksamhetens tjänsteområden omfattar allt från basservice till myndighetsuppgifter och vänder sig till hela universitetet.

Läs mer om våra förmåner och hur det är att jobba vid SLU på https://www.slu.se/om-slu/jobba-pa-slu/

Placering:
Uppsala

Anställningsform:
Tillsvidareanställning.  

Omfattning:
100%

Tillträde:
Enligt överenskommelse.

Ansökan:
Välkommen med din ansökan via ansökningsknappen nedan senast 2024-10-07.

Fackliga kontaktpersoner:
https://internt.slu.se/min-anstallning/facket/kontaktpersoner/

 


Sveriges lantbruksuniversitet (SLU) har en nyckelroll i utvecklingen för hållbart liv, grundad i vetenskap och utbildning. Genom vårt fokus på samspelen mellan människa, djur och ekosystem och ett ansvarsfullt brukande av naturresurserna bidrar vi till en hållbar samhällsutveckling och goda livsvillkor på vår planet. Huvudorter är Alnarp, Umeå och Uppsala, men verksamhet bedrivs också på forskningsstationer, försöksparker och utbildningsorter i hela landet.

SLU har drygt 3000 medarbetare, 5000 studenter och forskarstuderande och en omsättning på över tre miljarder kronor. Universitetet satsar på attraktiva miljöer på sina campusområden. Vi arbetar för en jämställd och inkluderande arbetsmiljö där öppna samtal mellan människor med olika erfarenheter lägger grunden för vetenskaplighet, kreativitet och utveckling. Vi välkomnar därför personer med olika bakgrunder och perspektiv att söka den aktuella anställningen.

Department of Plant Biology
About the position
A postdoctoral position in plant molecular biology and genetics is available at Prof. Markus Schmid's group at the Swedish University of Agriculture (SLU) in Uppsala, Sweden. Research in the Schmid lab focuses on the regulation of RNA splicing and how it contributes to temperature acclimation in plants. The project will explore whether transcriptome and proteome plasticity mediated by RNA splicing can be exploited to increase plant stress resilience and/or productivity. Our project will combine different methods in molecular biology, genetics, and genomics to investigate how temperature affects the RNA splicing capacity of plants, and what effect mutations in genes coding for the spliceosome have on temperature acclimation itself. We will apply these methods to two different plant models (Arabidopsis thaliana and hybrid aspen). We anticipate that our study will provide valuable insights into the role of RNA splicing in temperature acclimation and generate new tools to use RNA splicing for the improvement of plant resistance to temperature changes. Results from this project will contribute to mitigating the plants' reactions to environmental changes and thus to establishing sustainable agriculture.

Your profile
We are looking for a highly motivated candidate with a PhD in molecular biology, molecular genetics, functional genomics, cell biology, or related subjects deemed equivalent by the employer. The applicant should have a strong background in plant molecular biology and a competitive track record of previous scientific output as a first author. Applicants must have solid experience in standard molecular biological methods and plant genetics. Previous experience in the analysis of RNA splicing, genomic methods, or temperature responses in plants is an additional merit. The postdoc is expected to be a team player and enthusiastically drive a research project with strong initiative, creativity, and independent thinking. Excellent communication skills in both oral and written scientific English are expected. Since postdoctoral appointments are career-developing positions for junior researchers, priority will be given to candidates who have a doctoral degree not older than three years.

About us
The Department of Plant Biology offers a creative and stimulating international environment and is one of several departments that make up the ‘Uppsala BioCenter’. The department undertakes fundamental research on model organisms, agricultural crops, forest trees and bioenergy crops. Our main areas of research comprise the interaction of plants with microorganisms and other environmental stresses, plant growth and development, biotechnology and metabolic engineering, regulation of gene expression, population genetics, genome analysis, and the development of breeding systems. Species in use are model organisms such as Arabidopsis, Physcomitrella, tobacco, crops such as rapeseed, basket willow (Salix), potato, and cereals, and pathogens such as viruses, bacteria, and fungi/oomycetes. The department is responsible for basic and advanced courses in general and molecular genetics, cell biology, gene technology, plant physiology, plant breeding, plant biochemistry and biotechnology, and molecular interactions between plants and pathogens. In addition, the department contributes to various courses together with other departments.

Uppsala, Sweden ?s fourth-biggest city, has two universities and with more than 50 000 students a vibrant student atmosphere. It is located in the Greater Stockholm area and has an excellent connection to the Stockholm-Arlanda international airport.

For more information about the department visit: https://www.slu.se/en/departments/plant-biology-forest-genetics/

Read more about our benefits and working at SLU by visiting: https://www.slu.se/en/about-slu/work-at-slu/

Location:
Uppsala.

Form of employment:
Temporary employment 24 months, with the possibility of extension.

Scope:
100%.

Start date:
As agreed.

Application:
Please submit your application before deadline 30 September 2024. You can submit your application by clicking the button below.

Union representatives:
https://internt.slu.se/en/my-employment/employee-associations/kontaktpersoner-vid-rekrytering/

 


The Swedish University of Agricultural Sciences (SLU) has a key role in the development for sustainable life, based on science and education. Through our focus on the interaction between humans, animals and ecosystems and the responsible use of natural resources, we contribute to sustainable societal development and good living conditions on our planet. Our main campuses are located in Alnarp, Umeå and Uppsala, however, the university also operates at research stations, experimental forests and teaching sites throughout Sweden.

SLU has around 3,000 employees, 5,000 students and doctoral students and a turnover of over SEK 3 billion. We are investing in attractive environments on all of our campuses. We strive to provide a work environment characterised by inclusivity and gender equality, where different experiences generate conversations between people and pave the way for science, creativity and development. Therefore, we welcome applications from people with diverse backgrounds and perspectives.